Glucuronolactone is a naturally occurring substance that is an important structural component of nearly all connective tissues.Glucuronolactone is also found in many plant gums. glucuronolactone is hydrolyzed in the body (like butyrolactone) to glucuronic acid, which may be oxidized to glucaric acid, or isomerized to another hexuronic acid, so there is no reasonable toxicity mechanism.

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1.Glucuronolactone is metabolized to glucaric acid, xylitol, and L-xylulose, and humans may also be able to use glucuronolactone as a precursor for ascorbic acid synthesis
2.it is also used as a detoxicant The liver uses glucose to create glucuronolactone, which inhibits the enzyme B-glucuronidase (metabolizes glucuronides), which should cause blood-glucuronide levels to rise. Glucuronides combine with toxic substances, such as morphine and depot medroxyprogesterone acetate, by converting them to water-soluble glucuronide-conjugates which are excreted in the urine.
3.Glucuronolactone is a popular ingredient in energy drinks with claims that it detoxifies the body.
4.Glucurolactone can be combined with the liver and intestinal toxicants to form a non-toxic glucuronic acid conjugate, so it has liver and detoxification effects.
5.It is clinically used for the treatment of hepatitis, cirrhosis, jaundice, rheumatism, etc. It is also used as an antidote to food and drug poisoning.
6.The main role is to enhance the liver's detoxification function, restore or improve brain function, regulate immune function