Hydroxyproline is a nonessential amino acid, which means that it is manufactured from other amino acids in the liver; it does not have to be obtained directly through the diet.
Hydroxyproline is necessary for the construction of the body's major structural protein, collagen. Defects in carcinoma synthesis lead to easy bruising, physical bleeding, breakdown of connective tissue of the ligaments and tendons, and increased risk to blood vessel damage. Increased spill of hydroxyproline in The urine is generally associated with breakdown of connective tissue due to disease process and may also be a manifestation of vitamin C deficiency.

Function:
Hydroxyproline Functions in the Human Body:
Gives strength to the protein collagen in the bones, tendons, cartilage and skin.
Is produced by hydroxylation (adding hydroxil or [OH] groups) of proline, with the help of vitamin C. In vitamin C deficiency, proline cannot be converted to hydroxyproline, so collagen does not have enough strength to maintain skin integrity, which results in gum and skin bleeding and other symptoms of scurvy.
Hydroxyproline-Rich Foods:
ANIMAL FOODS: meat (deer, bison, beef, pork)